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Article

CYP3A7 protein expression is high in a fraction of adult human livers and partially associated with the CYP3A7*1C allele.

Pharmacogenetics and genomics - 1 Sept 2005

Sim Sarah C, Edwards Robert J, Boobis Alan R, Ingelman-Sundberg Magnus

Abstract excerpt

Previously, cytochrome P450 3A7 (CYP3A7), which constitutes the major CYP enzyme in fetal livers, has been considered a fetus-specific enzyme. However, CYP3A7 mRNA has recently been shown to be expressed at significant levels in a subset of adult human livers, several of which carry the CYP3A7*1C allele that contains the proximal PXR/CAR element of CYP3A4. The objective of this study was to investigate CYP3A7...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 16041241
DOI: 10.1097/01.fpc.0000171516.84139.89

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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