Article
Monoclonal antibodies that recognize antigens in human osteosarcoma cells and normal fetal osteoblasts.
Bone and mineral - 1 Sept 1993
Yamaguchi A, Kahn A J
Abstract excerpt
Four monoclonal antibodies (HOB-1-4) that react against human osteosarcoma cells (Saos-2) and human fetal osteoblasts in situ were developed by immunizing mice with Saos-2 cells. HOB-1 (IgG1, k) and HOB-2 (IgM, k) stain cytoplasmic antigens in Saos-2 cells, human authentic osteoblasts and occasional cells in liver, spleen and, in the instance of HOB-1, kidney and adrenal gland. On Western blotting of Saos-2 cell...
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