Article
Patterns of reactivity of four novel monoclonal antibodies (B72.3, DF3, B1.1 and B6.2) with cells in human malignant and benign effusions.
Acta cytologica - 1 Jan 2000
Szpak C A, Johnston W W, Lottich S C, Kufe D, Thor A, Schlom J
Abstract excerpt
The patterns of immunocytochemical reactivity produced in malignant and benign cells in effusions by staining with the monoclonal antibodies B72.3, DF3, B1.1 and B6.2 are reported. Using the mouse hybridoma methodology, these antibodies were raised against immunogens prepared from membrane-enriched extracts of metastatic carcinoma of the breast. Serial sections from the cell blocks of 20 benign effusions and 59...
Topics
- Adenocarcinoma
- Animals
- Antibodies, Monoclonal
- Ascitic Fluid
- Breast Neoplasms
- Carcinoma, Small Cell
- Carcinoma, Squamous Cell
- Epitopes
- Exudates and Transudates
- Female
- Humans