Article
Spatiotemporal assessment of fetal bovine osteoblast culture differentiation indicates a role for BSP in promoting differentiation.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research - 1 Apr 1998
Cooper L F, Yliheikkilä P K, Felton D A, Whitson S W
Abstract excerpt
Fetal bovine mandible-derived osteoblasts were cultured for the purpose of obtaining a spatiotemporal assessment of bone matrix protein expression during in vitro differentiation. The results obtained from electron microscopic, immunohistological, biochemical, and molecular biological analyses indicated that these primary cultured osteoblasts produce an abundant extracellular matrix which mineralizes during a...
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