A serum substitute promotes osteoblast-like phenotypic expression in cultured cells from chick calvariae.

doi:10.1016/0169-6009(91)90107-b

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Article

A serum substitute promotes osteoblast-like phenotypic expression in cultured cells from chick calvariae.

Bone and mineral - 1 Oct 1991

Ramp W K, Dillaman R M, Lenz L G, Gay D M, Roer R D, Ballard T A

Abstract excerpt

The effects of medium supplements were tested on embryonic chick calvarial cells in culture. Isolates were divided among four treatment groups: Nu-Serum, chicken serum, fetal bovine serum, or calf serum. Expression of the osteoblastic phenotype was assessed by cell morphology, DNA content, [3H]thymidine incorporation, lactate production, cellular and medium alkaline phosphatase activities, and collagen synthesis....

Topics

Alkaline Phosphatase
Analysis of Variance
Animals
Blood
Blood Substitutes
Cell Division
Cells, Cultured
Chick Embryo
Collagen
Culture Media
DNA
Endoplasmic Reticulum

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Microscopy, Electron

Organelles

Osteoblasts

Phenotype

Serum Albumin, Bovine

Thymidine

Source

Open in PubMed

Identifiers

PMID: 1747565
DOI: 10.1016/0169-6009(91)90107-b

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1747565-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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