Article
Monoclonal antibody 11-fibrau: a useful marker to characterize chondrocyte differentiation stage.
Biochemical and biophysical research communications - 26 Jan 2001
van Osch G J, van der Veen S W, Marijnissen W J, Verhaar J A
Abstract excerpt
The aim of this study was to determine the feasibility of discriminating between differentiated and dedifferentiated chondrocytes by using the Mab 11-fibrau. Mab 11-fibrau did not bind to differentiated chondrocytes in cartilage of human knee joint, auricle, or nasal septum. During monolayer culture, when cells dedifferentiate, the number of 11-fibrau positive cells gradually increased and reached up to 100%...
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