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Article

Nuclear matrix proteins distinguish normal diploid osteoblasts from osteosarcoma cells.

Cancer research - 1 Jan 1994

Bidwell J P, Fey E G, van Wijnen A J, Penman S, Stein J L, Lian J B, Stein G S

Abstract excerpt

Interrelationships between nuclear architecture and gene expression were examined by comparing the representation of nuclear matrix proteins in ROS 17/2.8 rat and MG-63 human osteosarcoma cells with those in normal diploid osteoblasts. The tumor-derived cells coexpress genes which are expressed in a sequential and mutually exclusive manner during the progressive stages of osteoblast differentiation. In...

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PMID: 8261453

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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