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Article

Translation of the human LINE-1 element, L1Hs.

15 Dec 1993

Abstract excerpt

Full-length RNA transcribed from the human LINE-1 (L1) element L1 Homo sapiens (L1Hs) has a 900-nt, G+C-rich, 5'-untranslated region (UTR). The 5' UTR is followed by two long open reading frames, ORF1 and ORF2, which are separated from each other by an inter-ORF region of 33 nt that includes two or three in-frame stop codons. We examine here the mechanism(s) by which the translation of L1Hs ORF1 and ORF2 is...

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PMID: 8265584
DOI: 10.1073/pnas.90.24.11533

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