Article
Antisense promoter of human L1 retrotransposon drives transcription of adjacent cellular genes.
Molecular and cellular biology - 1 Mar 2001
Speek M
Abstract excerpt
In the human genome, retrotranspositionally competent long interspersed nuclear elements (L1Hs) are involved in the generation of processed pseudogenes and mobilization of unrelated sequences into existing genes. Transcription of each L1Hs is initiated from its internal promoter but may also be driven from the promoters of adjacent cellular genes. Here I show that a hitherto unknown L1Hs antisense promoter (ASP)...
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