Article
Microsatellite instability in gastric cancer prone families.
Cancer letters - 6 Feb 1996
Sasaki A, Nagashima M, Shiseki M, Katai H, Maruyama K, Iwanaga R, Akiyama Y, Yuasa Y, Yokota J
Abstract excerpt
We examined for germ-line p53 mutations and microsatellite instability in three gastric cancer patients who had family histories of gastric cancer aggregation. Although no germ-line p53 mutation was detected in these three cases, the replication error (RER) phenotype was observed in two of them. One base deletion in the sequence of ten repeating adenines of the type II transforming growth factor-beta receptor...
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