Article
Characterisation of the osteoblastic phenotype by the use of differential hybridization.
Verhandlungen der Deutschen Gesellschaft fur Pathologie - 1 Jan 1990
Lanske B, Hesch R D, Kronenberg H M, Atkinson M J
Abstract excerpt
To identify genes active in cells of the osteoblast lineage we have begun to characterise the phenotype of the rat osteoblast-like osteosarcoma cell line ROS 17/2.8. We have used the method of differential hybridization to identify cDNA clones encoding mRNA species which are expressed in ROS 17/2.8 cells but not in a non-osteoblast-like osteosarcoma cell line (ROS 25/1). We have identified a number of gene...
Topics
- Animals
- Cell Line
- Cloning, Molecular
- Osteoblasts
- Osteosarcoma
- Phenotype
- RNA, Messenger
- Rats
- Sarcoma, Experimental