Article
Osteogenic protein-1 enhances phenotypic expression in ROS 17/2.8 cells.
The American journal of physiology - 1 Nov 1995
Kitten A M, Lee J C, Olson M S
Abstract excerpt
Osteogenic protein-1 (OP-1) stimulates bone morphogenesis in vivo and modulates osteoblast growth and differentiation in vitro. Treatment of ROS 17/2.8 cells with OP-1 resulted in a time- and concentration-dependent inhibition of [3H]thymidine incorporation. In contrast, OP-1 treatment stimulated...
Topics
- Alkaline Phosphatase
- Animals
- Bone Morphogenetic Protein 7
- Bone Morphogenetic Proteins
- Cell Differentiation
- Cell Division
- Cyclic AMP
- Cycloheximide
- DNA
- Dactinomycin
- Gene Expression
- Osteoblasts
- Parathyroid Hormone
- Phenotype
- Proteins
- RNA, Messenger
- Rats
- Receptors, Parathyroid Hormone