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Article

Relationship of cell growth to the regulation of tissue-specific gene expression during osteoblast differentiation.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology - 1 Oct 1990

Stein G S, Lian J B, Owen T A

Abstract excerpt

The relationship of cell proliferation to the temporal expression of genes characterizing a developmental sequence associated with bone cell differentiation can be examined in primary diploid cultures of fetal calvarial-derived osteoblasts by the combination of molecular, biochemical, histochemical, and ultrastructural approaches. Modifications in gene expression define a developmental sequence that has 1) three...

Topics

Animals
Base Sequence
Cell Differentiation
Cell Division
Cells, Cultured
Gene Expression Regulation
Histones
Molecular Sequence Data
Osteoblasts
Phenotype
Promoter Regions, Genetic

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Identifiers

PMID: 2210157
DOI: 10.1096/fasebj.4.13.2210157

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2210157-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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