Article
Relationship of cell growth to the regulation of tissue-specific gene expression during osteoblast differentiation.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology - 1 Oct 1990
Stein G S, Lian J B, Owen T A
Abstract excerpt
The relationship of cell proliferation to the temporal expression of genes characterizing a developmental sequence associated with bone cell differentiation can be examined in primary diploid cultures of fetal calvarial-derived osteoblasts by the combination of molecular, biochemical, histochemical, and ultrastructural approaches. Modifications in gene expression define a developmental sequence that has 1) three...
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