Expression of cell growth and bone phenotypic genes during the cell cycle of normal diploid osteoblasts and osteosarcoma cells.

doi:10.1002/jcb.240560221

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

Expression of cell growth and bone phenotypic genes during the cell cycle of normal diploid osteoblasts and osteosarcoma cells.

Journal of cellular biochemistry - 1 Oct 1994

McCabe L R, Last T J, Lynch M, Lian J, Stein J, Stein G

Abstract excerpt

Establishing regulatory mechanisms that mediate proliferation of osteoblasts while restricting expression of genes associated with mature bone cell phenotypic properties to post-proliferative cells is fundamental to understanding skeletal development. To gain insight into relationships between growth control and the developmental expression of genes during osteoblast differentiation, we have examined expression...

Topics

Actins
Alkaline Phosphatase
Animals
Bone Neoplasms
Bone and Bones
Cell Cycle
Cell Division
Cell Line
Cells, Cultured
Collagen
Diploidy
Extracellular Matrix

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Fetus

Gene Expression

Histones

Osteoblasts

Osteocalcin

Osteopontin

Source

Open in PubMed

Identifiers

PMID: 7829587
DOI: 10.1002/jcb.240560221

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7829587-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Expression of cell growth and bone phenotypic genes during the cell cycle of normal diploid osteoblasts and osteosarcoma cells.PMID 7829587Read ↗

Relationship of cell growth to the regulation of tissue-specific gene expression during osteoblast differentiation.Semantic proximity Read ↗

Concepts of osteoblast growth and differentiation: basis for modulation of bone cell development and tissue formation.Semantic proximity Read ↗

Nuclear matrix proteins distinguish normal diploid osteoblasts from osteosarcoma cells.Semantic proximity Read ↗

Progressive development of the rat osteoblast phenotype in vitro: reciprocal relationships in expression of genes associated with osteoblast proliferation and differentiation during formation of the bone extracellular matrix.Semantic proximity Read ↗

Expression of cell growth and bone specific genes at single cell resolution during development of bone tissue-like organization in primary osteoblast cultures.Semantic proximity Read ↗

Pleiotropic effects of vitamin D on osteoblast gene expression are related to the proliferative and differentiated state of the bone cell phenotype: dependency upon basal levels of gene expression, duration of exposure, and bone matrix competency in normal rat osteoblast cultures.Semantic proximity Read ↗

Developmental stage-specific cellular responses to vitamin D and glucocorticoids during differentiation of the osteoblast phenotype: interrelationship of morphology and gene expression by in situ hybridization.Semantic proximity Read ↗

TGF beta alters growth and differentiation related gene expression in proliferating osteoblasts in vitro, preventing development of the mature bone phenotype.Semantic proximity Read ↗

The Bone-specific Expression of Runx2 Oscillates during the Cell Cycle to Support a G1-related Antiproliferative Function in OsteoblastsSemantic proximity Read ↗

Development of the osteoblast phenotype: molecular mechanisms mediating osteoblast growth and differentiation.Semantic proximity Read ↗

Differential expression of the chromosomal high mobility group proteins 14 and 17 during the onset of differentiation in mammalian osteoblasts and promyelocytic leukemia cells.Semantic proximity Read ↗

Advances in the osteoblast lineageSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.