Ribosomal RNA identity elements for recognition by ricin and by alpha-sarcin: mutation in the putative CG pair that closes a GAGA tetraloop.

Article

Ribosomal RNA identity elements for recognition by ricin and by alpha-sarcin: mutation in the putative CG pair that closes a GAGA tetraloop.

Nucleic acids symposium series - 1 Jan 1993

Endo Y, Gluck A, Wool I G

Abstract excerpt

Alpha sarcin is a ribonuclease that cleaves the phosphodiester bond on the 3' side of G4325 in 28S rRNA; ricin A-chain is a RNA N-glycosidase that depurinates the 5' adjacent A4324. These single covalent modifications inactivate the ribosomes. An oligoribonucleotide that reproduces the structure...

Topics

Base Sequence
Binding Sites
Endoribonucleases
Fungal Proteins
Molecular Sequence Data
Mutation
Nucleic Acid Conformation
RNA, Ribosomal, 28S
Ricin

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