Article
Structure and stability of variants of the sarcin-ricin loop of 28S rRNA: NMR studies of the prokaryotic SRL and a functional mutant.
RNA (New York, N.Y.) - 1 Oct 1998
Seggerson K, Moore P B
Abstract excerpt
NMR has been used to examine the conformational properties of two variants of the sarcin-ricin loop (SRL) from eukaryotic 28S rRNA, which is essential for elongation factor interactions with the ribosome: (1) its bacterial homologue, which lacks two of the bases that flank the conserved 12-nt seq...
Topics
- Adenosine
- Animals
- Endoribonucleases
- Escherichia coli
- Fungal Proteins
- Hydrogen-Ion Concentration
- Mutation
- Nuclear Magnetic Resonance, Biomolecular
- Nucleic Acid Conformation
- Nucleic Acid Denaturation
- RNA, Ribosomal, 28S
- Rats
- Ricin
- Temperature