Article
Fission yeast Dss1 associates with the proteasome and is required for efficient ubiquitin-dependent proteolysis.
The Biochemical journal - 1 Jan 2006
Jossé Lyne, Harley Margaret E, Pires Isabel M S, Hughes David A
Abstract excerpt
Human DSS1 associates with BRCA2, a tumour suppressor protein required for efficient recombinational DNA repair, but the biochemical function of DSS1 is not known. Orthologues of DSS1 are found in organisms such as budding yeast and fission yeast that do not have BRCA2-related proteins, indicating that DSS1 has a physiological role independent of BRCA2. The DSS1 orthologue in Saccharomyces cerevisiae has been...
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