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Article

K-ras mutations in putative preneoplastic lesions in human colon.

Journal of the National Cancer Institute - 15 Dec 1993

Pretlow T P, Brasitus T A, Fulton N C, Cheyer C, Kaplan E L

Abstract excerpt

BACKGROUND: A mutation in c-K-ras (KRAS2) has long been implicated as one of the important early events in the development of a large proportion of human colon cancers. Aberrant crypt foci, putative preneoplastic lesions identified microscopically in wholemounts of colons, have been shown to occu...

Topics

Colonic Neoplasms
Genes, ras
Humans
Mutation
Precancerous Conditions

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 8246286
DOI: 10.1093/jnci/85.24.2004

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8246286-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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