HLA class I self peptides isolated from a T-cell leukemia reveal the allele-specific motif of HLA-B38.

doi:10.1111/j.1399-0039.1994.tb02361.x

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

HLA class I self peptides isolated from a T-cell leukemia reveal the allele-specific motif of HLA-B38.

Tissue antigens - 1 Aug 1994

Colovai A I, Suciu-Foca N, Baiulescu G E, Harris P E

Abstract excerpt

Naturally-processed self peptides bound to HLA class I molecules of a T-cell leukemia (HLA-A1, A31, B38, B58) were isolated for sequence analysis. Acid-eluted peptides were subjected to reversed-phase HPLC separation and single-fraction sequencing was performed by Edman degradation. The peptides were found to be mostly nonamers and could be grouped into three distinct structural motifs. One of the peptide groups...

Topics

Alleles
Amino Acid Sequence
Antigen Presentation
Autoantigens
Chromatography, High Pressure Liquid
Consensus Sequence
Gene Frequency
Genes, MHC Class I
HLA-A Antigens
HLA-A1 Antigen
HLA-B Antigens

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

HLA-B38 Antigen

Humans

Jews

Leukemia, Prolymphocytic, T-Cell

Molecular Sequence Data

Neoplastic Stem Cells

Peptide Fragments

Source

Open in PubMed

Identifiers

PMID: 7817380
DOI: 10.1111/j.1399-0039.1994.tb02361.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7817380-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

HLA class I self peptides isolated from a T-cell leukemia reveal the allele-specific motif of HLA-B38.PMID 7817380Read ↗

Identification and characterisation of peptide binding motifs of six autoimmune disease-associated human leukocyte antigen-class I molecules including HLA-B*39:06.Semantic proximity Read ↗

Comprehensive Analysis of the Naturally Processed Peptide Repertoire: Differences between HLA-A and B in the Immunopeptidome.Semantic proximity Read ↗

HLA binding of self-peptides is biased towards proteins with specific molecular functionsSemantic proximity Read ↗

Specificity and promiscuity among naturally processed peptides bound to HLA-DR alleles.Semantic proximity Read ↗

Allele-specific motifs revealed by sequencing of self-peptides eluted from MHC molecules. 1991.Semantic proximity Read ↗

Analysis of the structure of naturally processed peptides bound by class I and class II major histocompatibility complex molecules.Semantic proximity Read ↗

HLA-B15 peptide ligands are preferentially anchored at their C termini.Semantic proximity Read ↗

Identification of a dominant self-ligand bound to three HLA B44 alleles and the preliminary crystallographic analysis of recombinant forms of each complex.Semantic proximity Read ↗

Polymorphism in F pocket affects peptide selection and stability of type 1 diabetes-associated HLA-B39 allotypes.Semantic proximity Read ↗

Definition of specific peptide motifs for four major HLA-A alleles.Semantic proximity Read ↗

Naturally processed HLA class I bound peptides from c-myc-transfected cells reveal allele-specific motifs.Semantic proximity Read ↗

HLA-B16 antigens: sequence of the ST-16 antigen, further definition of two B38 subtypes and evidence for convergent evolution of B*3902.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.