Somatic mutations of the APC gene in precancerous lesion of the stomach.

doi:10.1093/hmg/2.9.1463

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Article

Somatic mutations of the APC gene in precancerous lesion of the stomach.

Human molecular genetics - 1 Sept 1993

Nakatsuru S, Yanagisawa A, Furukawa Y, Ichii S, Kato Y, Nakamura Y, Horii A

Abstract excerpt

The adenomatous polyposis coli (APC) gene, responsible for familial adenomatous polyposis, is also associated with development of sporadic tumors in digestive system as colon, stomach, or pancreas. In order to investigate whether or not APC mutations occur as an early genetic event during gastric...

Topics

Adenoma
Adenomatous Polyposis Coli
Base Sequence
DNA Mutational Analysis
DNA, Neoplasm
Frameshift Mutation
Genes, APC
Humans
Molecular Sequence Data
Mutation
Point Mutation
Precancerous Conditions
Sequence Deletion
Stomach Neoplasms

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