The DNA-binding domain of simian virus 40 tumor antigen has multiple functions.

doi:10.1128/JVI.67.12.7608-7611.1993

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Article

The DNA-binding domain of simian virus 40 tumor antigen has multiple functions.

Journal of virology - 1 Dec 1993

Wun-Kim K, Upson R, Young W, Melendy T, Stillman B, Simmons D T

Abstract excerpt

The DNA-binding domain of simian virus 40 tumor antigen has been previously shown to participate in a number of different activities. Besides being involved in binding to sequences at the viral replication origin, this domain appears to be required for nonspecific DNA binding, for structurally di...

Topics

Antigens, Viral, Tumor
DNA Helicases
DNA Replication
DNA, Viral
DNA-Binding Proteins
Mutation
Simian virus 40

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