Article
The zinc finger region of simian virus 40 large T antigen is needed for hexamer assembly and origin melting.
Journal of virology - 1 Jun 1991
Loeber G, Stenger J E, Ray S, Parsons R E, Anderson M E, Tegtmeyer P
Abstract excerpt
Simian virus 40 large T antigen contains a single sequence element with an arrangement of cysteines and histidines that is characteristic of a zinc finger motif. The finger region maps from amino acids 302 through 320 and has the sequence C-302 L K C-305 I K K E Q P S H Y K Y H-317 E K H-320. Previous genetic analysis has shown that the cysteine and histidine sequences and the contiguous S H Y K Y region in the...
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