Article
Distinct genetic pattern of mouse susceptibility to thyroiditis induced by a novel thyroglobulin peptide.
Immunogenetics - 1 Jan 1994
Carayanniotis G, Chronopoulou E, Rao V P
Abstract excerpt
Experimental autoimmune thyroiditis (EAT), induced by thyroglobulin (Tg) and adjuvant, is major histocompatibility complex-controlled and dependent on Tg-reactive T cells, but the immunopathogenic T-cell epitopes on Tg remain mostly undefined. We report here the thyroiditogenicity of a novel rat Tg peptide (TgP2; corresponding to human Tg amino acids 2695-2713), identified by algorithms as a site of putative...
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