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Article

Control of Her-2 tumor immunity and thyroid autoimmunity by MHC and regulatory T cells.

Cancer research - 15 Jul 2007

Jacob Jennifer B, Kong Yi-chi M, Meroueh Chady, Snower Daniel P, David Chella S, Ho Ye-Shih, Wei Wei-Zen

Abstract excerpt

Immune reactivity to self-antigens in both cancer and autoimmune diseases can be enhanced by systemic immune modulation, posing a challenge in cancer immunotherapy. To distinguish the genetic and immune regulation of tumor immunity versus autoimmunity, immune responses to human ErbB-2 (Her-2) and mouse thyroglobulin (mTg) were tested in transgenic mice expressing Her-2 that is overexpressed in several cancers,...

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Source

Identifiers

PMID: 17638915
DOI: 10.1158/0008-5472.CAN-06-4755

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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