Inferring the evolutionary histories of the Adh and Adh-dup loci in Drosophila melanogaster from patterns of polymorphism and divergence.

doi:10.1093/genetics/127.3.565

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Article

Inferring the evolutionary histories of the Adh and Adh-dup loci in Drosophila melanogaster from patterns of polymorphism and divergence.

Genetics - 1 Mar 1991

Kreitman M, Hudson R R

Abstract excerpt

The DNA sequences of 11 Drosophila melanogaster lines are compared across three contiguous regions, the Adh and Adh-dup loci and a noncoding 5' flanking region of Adh. Ninety-eight of approximately 4750 sites are segregating in the sample, 36 in the 5' flanking region, 38 in Adh and 24 in Adh-dup...

Topics

Alcohol Dehydrogenase
Animals
Base Sequence
Biological Evolution
Drosophila melanogaster
Gene Frequency
Genetic Variation
Molecular Sequence Data
Multigene Family
Polymerase Chain Reaction
Polymorphism, Genetic
Polymorphism, Restriction Fragment Length
Repetitive Sequences, Nucleic Acid

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Identifiers

PMID: 1673107
DOI: 10.1093/genetics/127.3.565
PMCID: PMC1204384

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-1673107-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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