Article
Two types of cis-trans compensation in the evolution of transcriptional regulation.
Proceedings of the National Academy of Sciences of the United States of America - 13 Sept 2011
Takahasi K Ryo, Matsuo Takashi, Takano-Shimizu-Kouno Toshiyuki
Abstract excerpt
Because distant species often share similar macromolecules, regulatory mutations are often considered responsible for much of their biological differences. Recently, a large portion of regulatory changes has been attributed to cis-regulatory mutations. Here, we examined an alternative possibility that the putative contribution of cis-regulatory changes was, in fact, caused by compensatory action of cis- and...
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