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Article

Exploring RNA conformational space under sparse distance restraints.

Scientific reports - 10 Mar 2017

Taylor William R, Hamilton Russell S

Abstract excerpt

We show that the application of a small number of restraints predicted by coevolution analysis can provide a powerful restriction on the conformational freedom of an RNA molecule. The greatest degree of restriction occurs when a contact is predicted between the distal ends of a pair of adjacent stemloops but even with this location additional flexibilities in the molecule can mask the contribution. Multiple...

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Identifiers

PMID: 28281575
DOI: 10.1038/srep44074
PMCID: PMC5345030

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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