Article
Compensatory neutral mutations and the evolution of RNA.
Genetica - 1 Jan 1998
Higgs P G
Abstract excerpt
There are many examples of RNA molecules in which the secondary structure has been strongly conserved during evolution, but the base sequence is much less conserved, e.g., transfer RNA, ribosomal RNA, and ribonuclease P. A model of compensatory neutral mutations is used here to describe the evolution of the base sequence in RNA helices. There are two loci (i.e., the two sides of the pair) with four alleles at...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
