Compensatory neutral mutations and the evolution of RNA.

Article

Compensatory neutral mutations and the evolution of RNA.

Genetica - 1 Jan 1998

Higgs P G

Abstract excerpt

There are many examples of RNA molecules in which the secondary structure has been strongly conserved during evolution, but the base sequence is much less conserved, e.g., transfer RNA, ribosomal RNA, and ribonuclease P. A model of compensatory neutral mutations is used here to describe the evolu...

Topics

Alleles
Animals
Base Composition
Base Sequence
Evolution, Molecular
Humans
Mathematics
Models, Genetic
Models, Statistical
Mutation
Nucleic Acid Conformation
RNA
RNA, Transfer
Sequence Alignment
Sequence Homology, Nucleic Acid

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