Article
Identification of the PPARA locus on chromosome 22q13.3 as a modifier gene in familial combined hyperlipidemia.
Molecular genetics and metabolism - 1 Dec 2002
Eurlings Petra M H, van der Kallen Carla J H, Geurts Jan M W, Flavell David M, de Bruin Tjerk W A
Abstract excerpt
Familial combined hyperlipidemia (FCHL) is a common genetic lipid disorder that is present in 10% of patients with premature coronary artery disease (CAD). It was the objective of the present study to evaluate the possible involvement of the PPARA locus in the pathophysiology of FCHL. Mutation de...
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