Article
Bimodality of plasma apolipoprotein B levels in familial combined hyperlipidemia.
Atherosclerosis - 1 Jan 1992
Austin M A, Horowitz H, Wijsman E, Krauss R M, Brunzell J
Abstract excerpt
To investigate possible genetic influences on plasma apolipoprotein (apo) B levels in familial combined hyperlipidemia (FCHL), commingling analysis was performed on data from seven large kindreds, including 183 individuals. The overall frequency distribution of apo B was skewed and was compatible with the presence of two normally distributed subdistributions (mean values, 117 and 172 mg/dl). The analysis was...
Topics
- Adolescent
- Adult
- Apolipoproteins B
- Female
- Humans
- Hyperlipidemia, Familial Combined
- Lipids
- Lipoproteins, LDL
- Male
- Phenotype