Article
A major gene effect on fasting insulin and insulin sensitivity in familial combined hyperlipidemia.
Diabetes - 1 Oct 2001
Pihlajamäki J, Austin M, Edwards K, Laakso M
Abstract excerpt
The most common inherited dyslipidemia, familial combined hyperlipidemia (FCHL), is associated with insulin resistance. Whether insulin sensitivity in these families is inherited is not known. Therefore, we investigated the inheritance of insulin sensitivity in 352 nondiabetic family members from 37 families with FCHL, 105 of whom had undergone testing using the hyperinsulinemic-euglycemic clamp technique for the...
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