Lack of evidence for linkage between low-density lipoprotein subclass phenotypes and the apolipoprotein B locus in familial combined hyperlipidemia.

doi:10.1002/gepi.1370080502

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Article

Lack of evidence for linkage between low-density lipoprotein subclass phenotypes and the apolipoprotein B locus in familial combined hyperlipidemia.

Genetic epidemiology - 1 Jan 1991

Austin M A, Wijsman E, Guo S W, Krauss R M, Brunzell J D, Deeb S

Abstract excerpt

Low-density lipoprotein (LDL) subclass phenotype B, characterized by a predominance of small, dense LDL particles, appears to be a genetically influenced risk factor for coronary heart disease. Phenotype B, as determined by gradient gel electrophoresis, appears to be inherited in a manner consist...

Topics

Alleles
Apolipoproteins B
Female
Genetic Linkage
Humans
Hyperlipidemia, Familial Combined
Lipoproteins, LDL
Male
Pedigree
Phenotype

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