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Article

Ribonucleotide reductases: radical enzymes with suicidal tendencies.

Biochemical Society transactions - 1 Aug 1993

Booker S, Broderick J, Stubbe J

Abstract excerpt

Ribonucleotide reductases isolated from E. coli and from L. leichmannii differ considerably in their primary and quaternary structures, as well as in their cofactor requirements. Despite these differences, studies with the wt enzymes and the normal substrate, and with the wt enzymes and a variety of mechanism-based inhibitors, demonstrate amazing mechanistic similarities between the two reductases. Recent studies...

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Identifiers

PMID: 8224499
DOI: 10.1042/bst0210727

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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