Article
Exon skipping gives rise to alternatively spliced forms of the estrogen receptor in breast tumor cells.
Breast cancer research and treatment - 1 Jan 1993
Miksicek R J, Lei Y, Wang Y
Abstract excerpt
We have previously described three messenger RNA variants coding for the human estrogen receptor (ER) [1]. These variants were identified using the polymerase chain reaction to perform directed cloning of ER cDNAs synthesized from polyadenylated RNA extracted from the human breast cancer cell line T47D. Each of the variants is characterized by the precise deletion of a single exon within the protein coding region...
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