Oestrogen receptor mutants and variants in breast cancer.

doi:10.1016/s0959-8049(97)00100-7

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Article

Oestrogen receptor mutants and variants in breast cancer.

European journal of cancer (Oxford, England : 1990) - 1 Jul 1997

Dowsett M, Daffada A, Chan C M, Johnston S R

Abstract excerpt

Oestrogen receptor (ER) status is the only biochemical predictive factor which is routinely measured in breast carcinomas. ER gene mutations can profoundly change the biochemical activity of the protein. If these occurred in vivo, they could be expected to affect breast cancer risk or phenotype,...

Topics

Biomarkers, Tumor
Breast Neoplasms
Female
Humans
Mutation
RNA, Messenger
RNA, Neoplasm
Receptors, Estrogen

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