Article
Novel mutations in the estrogen receptor messenger RNA in human breast cancers.
The Journal of clinical endocrinology and metabolism - 1 Apr 1996
Murphy L C, Wang M, Coutt A, Dotzlaw H
Abstract excerpt
One mechanism that has been suggested to play a role in the progression of human breast cancer from hormone dependence to independence is the expression or altered expression of mutant and/or variant forms of estrogen receptor (ER). Two major types of variant ER messenger (m)RNA have been identif...
Topics
- Base Sequence
- Breast Neoplasms
- DNA Primers
- DNA Transposable Elements
- Exons
- Female
- Genetic Variation
- Humans
- Molecular Sequence Data
- Mutation
- Polymerase Chain Reaction
- Protein Biosynthesis