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Article

Estrogen receptor mRNA splice variants in pre- and postmenopausal human endometrium and endometrial carcinoma.

Gynecologic oncology - 1 Apr 1997

Rice L W, Jazaeri A A, Shupnik M A

Abstract excerpt

Breast cancer tissue has been shown to contain alternatively spliced estrogen receptor (ER) mRNA variants which may result in alternate ER proteins. These ER variants lack specific functional domains and may alter breast cancer cells responses to both estrogen and antiestrogens. Specifically, ER variants might play a role in Tamoxifen resistance in breast cancer patients, as well as the development of endometrial...

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Identifiers

PMID: 9103405
DOI: 10.1006/gyno.1997.4623

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

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Estrogen receptor mRNA splice variants in pre- and postmenopausal human endometrium and endometrial carcinoma.PMID 9103405Read ↗

Estrogen receptor variants are present in many normal human tissues.Semantic proximity Read ↗

Prevalence of estrogen receptor variant messenger RNAs in human breast cancer.Semantic proximity Read ↗

Identification of novel transcript variants of estrogen receptor α, β and progesterone receptor gene in human endometrium.Semantic proximity Read ↗

Estrogen receptor variants in epithelial compartment of normal human breast.Semantic proximity Read ↗

Estrogen receptor-beta mRNA variants in human and murine tissues.Semantic proximity Read ↗

Expression of an estrogen receptor alpha variant protein in cell lines and tumors.Semantic proximity Read ↗

Expression of an estrogen receptor alpha variant protein in cell lines and tumors.Semantic proximity Read ↗

Estrogen receptor mRNA splice variants produced from the distal and proximal promoter transcripts.Semantic proximity Read ↗

A novel estrogen receptor variant mRNA lacking exons 4 to 6 in breast carcinoma.Semantic proximity Read ↗

Estrogen receptor-alpha messenger RNA variants that lack exon 5 or exon 7 are coexpressed with wild-type form in human endometrium during all phases of the menstrual cycle.Semantic proximity Read ↗

Tissue-dependent expression of a novel splice variant of the human oestrogen receptor.Semantic proximity Read ↗

Exon skipping gives rise to alternatively spliced forms of the estrogen receptor in breast tumor cells.Semantic proximity Read ↗

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