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Article

A cosmid-based system for constructing mutants of herpes simplex virus type 1.

Virology - 1 Nov 1993

Cunningham C, Davison A J

Abstract excerpt

Cosmids containing large fragments of herpes simplex virus type 1 DNA were prepared using a vector that allows intact inserts to be excised using the restriction endonuclease PacI. Two independent sets (A and B) of five cosmids were identified whose inserts overlap and represent the entire viral genome, and set C was obtained by replacing two cosmids in set B. Each set gave rise to viral plaques when digested...

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Identifiers

PMID: 8212547
DOI: 10.1006/viro.1993.1572

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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