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Article

Isolation of a herpes simplex virus type 1 mutant deleted for the essential UL42 gene and characterization of its null phenotype.

Journal of virology - 1 Feb 1991

Johnson P A, Best M G, Friedmann T, Parris D S

Abstract excerpt

We isolated a cell line, designated V9, stably transformed with the herpes simplex virus type 1 (HSV-1) UL42 gene, which is one of seven genes required in trans for the replication of plasmids containing an HSV origin of replication (C. A. Wu, N. J. Nelson, D. J. McGeoch, and M. D. Challberg, J. Virol. 62:435-443, 1988). V9 cells inducibly expressed the product of the UL42 gene, the 65-kDa DNA-binding protein...

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Identifiers

PMID: 1846193
DOI: 10.1128/JVI.65.2.700-710.1991
PMCID: PMC239809

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