Article
Comparison of full genome sequences between two hepatitis B virus strains with or without preC mutation (A1896) from a single Korean hepatocellular carcinoma patient.
Journal of microbiology and biotechnology - 1 Apr 2007
Kim Hong, Jee Youngmee, Mun Ho-Suk, Song Byung-Cheol, Park Joo-Hee, Hyun Jin-Won, Hwang Eung-Soo, Cha Chang-Yong, Kook Yoon-Hoh, Kim Bum-Joon
Abstract excerpt
This report describes the full-length sequences of 2 HBV clones from a hepatocellular carcinoma (HCC) patient, one with preC mutation (1896A) and the other without preC mutation. The high level of discrepancy in mutation frequency between these 2 strains was observed in the Core (C) region among 4 ORFs. These data support previous results that Korean HBV strains, belonging to genotype C2, are prone to mutations....
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