Article
Analysis of HLA-class-II-encoded antigen-processing genes TAP1 and TAP2 in primary biliary cirrhosis.
The Quarterly journal of medicine - 1 Apr 1994
Gregory W L, Daly A K, Dunn A N, Cavanagh G, Idle J R, James O F, Bassendine M F
Abstract excerpt
The search for genes involved in the aetiology of primary biliary cirrhosis (PBC) has centred on the major histocompatibility complex (MHC) on chromosome 6. Genotyping studies have confirmed an association with HLA class II allele DR8. We investigated polymorphisms in two newly identified genes (...
Topics
- Base Sequence
- Gene Frequency
- Genes, MHC Class II
- Genotype
- Haplotypes
- Histocompatibility Antigens Class II
- Humans
- Liver Cirrhosis, Biliary
- Molecular Sequence Data
- Polymorphism, Genetic