Article
Human leukocyte antigen class II alleles in Caucasian women with primary biliary cirrhosis.
Tissue antigens - 1 Feb 2005
Mullarkey M E, Stevens A M, McDonnell W M, Loubière L S, Brackensick J A, Pang J M, Porter A J, Galloway D A, Nelson J L
Abstract excerpt
In the current study, we investigated human leukocyte antigen (HLA) class II alleles in Caucasian women with primary biliary cirrhosis (PBC), a disease that preferentially affects women. Alleles of DRB1, DQA1, and DQB1 were determined by DNA-based HLA typing for women with PBC (n = 72) and healthy women (n = 381). All study subjects were Caucasian. HLA DRB1*08 was significantly increased in women with PBC...
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