Article
Alleles and haplotypes of the MHC-encoded ABC transporters TAP1 and TAP2.
Immunogenetics - 1 Jan 1993
Powis S H, Tonks S, Mockridge I, Kelly A P, Bodmer J G, Trowsdale J
Abstract excerpt
TAP1 and TAP2 are two major histocompatibility complex (MHC) genes, located between HLA-DP and -DQ, whose products form a transporter molecule involved in endogenous antigen processing. Polymorphic residues have been described in both genes and, in this study, we have identified another polymorphic site within the adenosine triphosphate (ATP)-binding domain of TAP2. We have used the amplification refractory...
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