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Article

Differentiation stages of childhood acute lymphoblastic leukemias with p53 mutations.

Leukemia - 1 Jun 1994

Felix C A, Wasserman R, Lange B J, Brown D L, Nau M M, Cole D E, Minna J D, Poplack D G

Abstract excerpt

Based upon in vitro evidence of p53 involvement in lymphoid differentiation, we assessed immunoglobulin (Ig) and T-cell receptor (TCR) genes in five acute lymphoblastic leukemias (ALLs) with, and 24 ALLs without p53 mutations to compare their genotypic stages. Using Southern blot analysis and com...

Topics

Adolescent
Adult
Burkitt Lymphoma
Cell Differentiation
Child
Child, Preschool
Codon
Genes, p53
Genotype
Humans
Immunophenotyping
Infant
Leukemia-Lymphoma, Adult T-Cell

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mutation

Neoplasm Staging

Precursor Cell Lymphoblastic Leukemia-Lymphoma

Source

Identifiers

PMID: 8207991

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8207991-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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