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Article

Exon 5 mutations in the p53 gene in relapsed childhood acute lymphoblastic leukemia.

Leukemia research - 1 Aug 1997

Blau O, Avigad S, Stark B, Kodman Y, Luria D, Cohen I J, Zaizov R

Abstract excerpt

Thirty seven children with relapsed acute lymphoblastic leukemia (ALL), 25 B-lineage and 12 T-lineage, were analyzed for p53 alterations at different stages of the disease. Loss of heterozygosity (LOH) was detected in the relapse phase in three patients. p53 mutations were identified by single strand conformation polymorphism (SSCP) and sequencing analyzes in seven of the 37 ALL patients (19%); three B-lineage...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 9379679
DOI: 10.1016/s0145-2126(97)80032-x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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