Article
Stages of T-cell receptor protein expression in T-cell acute lymphoblastic leukemia.
Blood - 1 Apr 1991
Campana D, van Dongen J J, Mehta A, Coustan-Smith E, Wolvers-Tettero I L, Ganeshaguru K, Janossy G
Abstract excerpt
In this study five monoclonal antibodies (MoAbs) to T-cell receptor (TCR) proteins (WT31, alpha F1, beta F1, TCR delta-1 and delta TCS-1) were used to identify discrete maturative stages in 40 cases of T-cell acute lymphoblastic leukemia (T-ALL). These MoAbs reacted exclusively with CD3+ T cells...
Topics
- Adult
- Antibodies, Monoclonal
- Antigens, CD
- Antigens, Differentiation, T-Lymphocyte
- CD3 Complex
- Female
- Fetus
- Gene Rearrangement, T-Lymphocyte
- Humans
- Leukemia-Lymphoma, Adult T-Cell
- Liver
- Phenotype
- Pregnancy
- Receptors, Antigen, T-Cell
- Reference Values