Article
Lineage alteration in precursor B cell acute lymphoblastic leukemia following T cell lymphoblastic lymphoma.
Leukemia - 1 Dec 1992
Gemma N W, Lovell M A, Bringelsen K A, Williams M E
Abstract excerpt
A 10-year-old girl was diagnosed with lymphoblastic lymphoma; staging evaluation revealed a large mediastinal mass and normal peripheral blood and bone marrow morphology. Tumor cell immunologic marker analysis and Southern blot gene rearrangement studies demonstrated a T-cell lineage. She achieved a complete remission following multi-agent chemotherapy; however, 19 months following initial diagnosis while on...
Topics
- Burkitt Lymphoma
- Child
- Female
- Gene Rearrangement, B-Lymphocyte, Heavy Chain
- Gene Rearrangement, B-Lymphocyte, Light Chain
- Gene Rearrangement, beta-Chain T-Cell Antigen Receptor
- Gene Rearrangement, gamma-Chain T-Cell Antigen Receptor
- Genotype
- Humans
- Mediastinal Neoplasms
