Article
Increased frequency of TAP2B in early onset pauciarticular juvenile chronic arthritis.
Annals of the rheumatic diseases - 1 Apr 1994
Donn R P, Davies E J, Holt P L, Thomson W, Ollier W
Abstract excerpt
OBJECTIVES: To determine whether polymorphisms of the TAP genes, which lie within the major histocompatibility complex (MHC), are associated with juvenile chronic arthritis (JCA). METHODS: Eighty five JCA patients and 166 white controls were typed for the TAP gene alleles using ARMS-PCR. The same populations were analysed for DRB1 and DPB1 alleles using PCR-SSO typing. RESULTS: TAP2B was increased in early onset...
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