Article
Increased frequency of TAP2B in early onset pauciarticular juvenile chronic arthritis.
Annals of the rheumatic diseases - 1 Apr 1994
Donn R P, Davies E J, Holt P L, Thomson W, Ollier W
Abstract excerpt
OBJECTIVES: To determine whether polymorphisms of the TAP genes, which lie within the major histocompatibility complex (MHC), are associated with juvenile chronic arthritis (JCA). METHODS: Eighty five JCA patients and 166 white controls were typed for the TAP gene alleles using ARMS-PCR. The same...
Topics
- ATP Binding Cassette Transporter, Subfamily B, Member 3
- ATP-Binding Cassette Transporters
- Alleles
- Arthritis, Juvenile
- Carrier Proteins
- Child
- Child, Preschool
- Female
- Gene Frequency
- HLA-DP Antigens
- HLA-DP beta-Chains
- HLA-DR Antigens
- HLA-DRB1 Chains
- Histocompatibility Antigens Class II
- Humans
- Linkage Disequilibrium
- Male
- Polymerase Chain Reaction