Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

HLA-DP/DR interaction in early onset pauciarticular juvenile chronic arthritis.

Immunogenetics - 1 Jan 1993

Paul C, Schoenwald U, Truckenbrodt H, Bettinotti M P, Brünnler G, Keller E, Nevinny-Stickel C, Yao Z, Albert E D

Abstract excerpt

We investigated the polymorphic second exon of the HLA-DPB1 and HLA-DRB1 genes, using in vitro DNA amplification by polymerase chain reaction (PCR) and oligonucleotide hybridization in 136 patients with early onset pauciarticular juvenile chronic arthritis (EOPA-JCA) and 199 healthy controls. The analysis of the HLA-DRB1 system revealed that most of the DRB1 alleles are not indifferent with respect to...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Base Sequence
Share to Gene Frequency

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Haplotypes

Share to HLA-DP Antigens

Share to HLA-DR Antigens

Share to Molecular Sequence Data

Share to Oligodeoxyribonucleotides

Source

Identifiers

PMID: 8436419
DOI: 10.1007/BF00222468

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

HLA-DP/DR interaction in early onset pauciarticular juvenile chronic arthritis.PMID 8436419Read ↗

Susceptible and protective major histocompatibility complex class II alleles in early-onset pauciarticular juvenile chronic arthritis.Semantic proximity Read ↗

Interaction between HLA-DR and HLA-DP, and between HLA and interleukin 1 alpha in juvenile rheumatoid arthritis indicates heterogeneity of pathogenic mechanisms of the disease.Semantic proximity Read ↗

A distinct HLA-DRw8 haplotype characterizes patients with juvenile rheumatoid arthritis.Semantic proximity Read ↗

Immunogenetics of juvenile chronic arthritis. I. HLA interaction between A2, DR5/8-DR/DQ, and DPB1*0201 is a general feature of all subsets of early onset pauciarticular juvenile chronic arthritis II. DPB1 polymorphism plays a role in systemic juvenile chronic arthritis.Semantic proximity Read ↗

A model for the role of HLA-DQ molecules in the pathogenesis of juvenile chronic arthritis.Semantic proximity Read ↗

HLA class I/class II interaction in early onset pauciarticular juvenile chronic arthritis.Semantic proximity Read ↗

Subtypes of HLA-DRB1*03, *08, *11, *12, *13 and *14 in early onset pauciarticular juvenile chronic arthritis (EOPA) with and without iridocyclitis.Semantic proximity Read ↗

Immunogenetics of rheumatoid arthritis and juvenile arthritis.Semantic proximity Read ↗

HLA antigens in juvenile arthritis. Pauciarticular and polyarticular juvenile arthritis are immunogenetically distinct.Semantic proximity Read ↗

HLA and juvenile rheumatoid arthritis.Semantic proximity Read ↗

HLA-DPB1*0301 is a major risk factor for rheumatoid factor-negative adult rheumatoid arthritis.Semantic proximity Read ↗

Class I associations and frequencies of class II HLA-DRB alleles by RFLP analysis in children with rheumatoid-factor-negative juvenile chronic arthritis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.