Article
HLA antigens in juvenile arthritis. Pauciarticular and polyarticular juvenile arthritis are immunogenetically distinct.
Arthritis and rheumatism - 1 Dec 1990
Fernandez-Viña M A, Fink C W, Stastny P
Abstract excerpt
Using DNA techniques, we investigated the role of HLA-DR, DQ, and DP alleles in susceptibility to juvenile arthritis (JA). We studied 2 groups of patients with JA having a different disease prognosis and course. The pauciarticular form is usually benign, while the polyarticular disease frequently...
Topics
- Adolescent
- Alleles
- Antibodies, Antinuclear
- Arthritis, Juvenile
- Base Sequence
- Child
- Child, Preschool
- Female
- Gene Frequency
- HLA Antigens
- HLA-DP Antigens
- HLA-DP beta-Chains
- HLA-DQ Antigens
- HLA-DR Antigens
- HLA-DR Serological Subtypes
- Humans
- Male
- Molecular Sequence Data